BRAVE B-Curious
Monitor (nano)particle behavior in real-time
Do you want to make groundbreaking discoveries and gain deep insights into your samples? With BRAVE B-Curious you have the perfect tool for these discoveries. You will get nanoparticle characterization results like never before. Prepare to be surprised: conventional methods of particle analysis like DLS, NTA or Laser Diffraction only show a fraction of what the revolutionary technology of BRAVE B-Curious can measure.
The patented OF2i® method gives you detailed insights into all the particle populations of your sample and tracks changes in nanoparticle size distributions and particle concentrations in real-time and continuously. You will get a better understanding of particle behavior and learn more about the processes. All measurement results are representative and statistically relevant. As a true pioneer you can raise your research to a new level with BRAVE B-Curious.
Everyone who has worked with the conventional methods for nanoparticle characterization in the lab already is familiar with the feeling of discontent – or even frustration – resulting from the limits of measurability. Dynamic Light Scattering, Nanoparticle tracking Analysis and Laser Diffraction only allow limited insights into the actual particle behavior and typically struggle to measure ultra-low particle concentrations.
Get ready for BRAVE B-Curious, which lets you analyze particle behavior continuously and in real-time over minutes and hours. The results have single-particle sensitivity based on measurement of up to 1000 particles per minute. This makes them statistically relevant and representative of the whole particle population. With this time-resolved approach you can monitor kinetic processes like aggregation, condensate formation, agglomeration, dissolution or dissociation and analyze them in real-time and in one continuous measurement.
With BRAVE B-Curious you can:
BRAVE B-Curious helps you overcome many of the limitations of conventional methods. For the first time ever, you can monitor particles in real-time and continuously over a time period you define. You get unprecedented insights into your processes and the behavior of particle populations – an open door to groundbreaking discoveries.
Particle size distribution (actual D-values)
Sample behavior such as dissolution, dissociation, condensate formation, crystallization and protein-protein interactions
Anomalies, aggregates, large-particle tails and other oversized particles
Particle concentrations (even down to a few particles per milliliter)
Particle size with single-particle sensitivity
Send us your sample - and we'll do the rest
Find out whether OF2i® measurements are the answer to your particle challenges!
Get in touch, we’ll organize measurements on your sample(s) and send you a detailed measurement report.
This is the first (non-binding) step to a feasibility study. Open the door to deeper insights today!
We built BRAVE B-Curious as a modular platform, so you can configure it to perfectly suit your needs. Our experts will work together with you on a custom-tailored setup. Your BRAVE B-Curious will be aligned with your needs and ideal for your research – with the possibility of future upgrades and additional modules at a later date.
Module for concentration determination
Allows the detection of ultra-low concentrations (e.g. nanoplastics or water for injections) at particle concentrations down to a few particles per milliliter.
Module for time-resolved sizing
Allows the monitoring of PSD continuously and directly out of containers. This way you can monitor sample behavior such as agglomeration, formation, dissolution, aggregation, dissociation, self-assembly and more. Detection range: 50 nm* to 5 µm* (*sample-dependent)
Module for size range extension
Allows the detection of large-particle tails, LPC, aggregation behaviors and anomalies. Detection range: 50 nm* to 50 µm* (*sample-dependent)
Module for particle analytics
Allows the identification and characterization of particle populations via Raman spectroscopy. Adding this module makes a BRAVE B-Elementary device.
Module for low-volume sizing
Allows the determination of PSD from low volumes, starting at 20 µl (sample-dependent)
Module for Raman tweezers
Allows the trapping of particle populations for characterization with Raman spectroscopy. Adding this module makes a BRAVE B-Elementary device.
BRAVE B-Curious is the ideal instrument for groundbreaking research in the field of nanoparticle characterization and offers a new approach. You obtain unprecedented insights into particle behavior, sample processes and a complete overview of the particle populations.
BRAVE B-Curious implements a new approach to particle analysis: OF2i®. This new principle of particle characterization uses opto-fluidic forces to accelerate, decelerate, trap or even redirect nanoparticles. OF2i® (OptoFluidic Force Induction) allows you to measure particle size, particle size distributions and particle concentrations more exactly than ever before – with single-particle sensitivity and statistical relevance. Unlike established methods, the patented OF2i® method is not dependent on Brownian motion. With OF2i® you measure continuously and in real-time and can even resolve complex, polydisperse systems.
H.A.N.S. supports you with:
In its development phase, BRAVE B-Curious was already in use by some selected partners at universities and research institutes. As of March 2023 you can order your own BRAVE B-Curious. Contact us or book a live demonstration and we will answer all your questions. What are you waiting for? It’s time to make groundbreaking discoveries!
You are just one click away from revolutionizing your research!
A number of methods for particle characterization are available. These all have their advantages and disadvantages and are suited for different areas of application. BRAVE B-Curious with the patented OF2i® method has a number of advantages over conventional approaches.
Electron microscopes deliver impressive high-resolution images. Despite offering in-depth analysis, BRAVE B-Curious still has benefits compared to this method of particle analysis.
If you are used to analyzing particles with Dynamic Light Scattering, you can look forward to next-level results and benefits such as:
Our expertise
As a partner in the MOZART project (MOZART for safe & sustainable by-design metallic coatings & engineered surfaces (RIA)), we received funding from the European Commission as part of the EU Horizon 2020 program.