Take a look at how OF2i® and our other BRAVE innovations are in use in research.
BRAVE Analytics’ nanoparticle analyzer and online particle sensor provide a way to determine when aggregation starts to occur. It monitors the progression of aggregation as it happens via OF2i® and static light scattering signals[1] and delivers results in real-time, eliminating the delay inherent in waiting for offline measurements.
Reference: [1] Imaging the scattered light of a nanoparticle through a cylindrical capillary. Ulrich Hohenester, Christian Neuper, Marko Šimić, and Christian Hill. Nanophotonics, 13(4):457–463, 2024.
These time-resolved measurements on different concentrations of proteins and RNA reveal the kinetics of LLPS processes and allow deeper insights than ever before.
Phase inversion is an important industrial process to make stable emulsions e.g. for personal care products. After phase inversion, the liquid-in-liquid dispersions have a droplet size in the nano-range. This brings a number of benefits due to e.g. high surface area per volume, high stability and other desirable properties. However, it is not always easy to control and predict the final droplet size during the production process.
To enable low-budget detection of car tire nanopollutants in surface water, Assistant Professor Gregor Marolt and his research group at University of Ljubljana are developing an innovative screen-printed sensor technology. He needed a quick and reliable way to verify his measurements.
The goal was to quantify the differences between differently filtrated samples. During the measurement over 300 particles were measured with single-particle sensitivity, also capturing unknown bigger particles (probably agglomerates).
e.g. cryo-EM investigations.
Building on the above experiments, we used Raman spectroscopy to distinguish between:
Stay tuned for the report.
To be continued…
Researchers at an Austrian university used BRAVE B-Curious to continuously measure plastic particle contamination and the leaching processes of different polypropylene bottles and compared them to glass bottles.
One of the takeaways from the experiments is that particles are leaching into the liquid as soon as the liquid is in the plastic bottle.
The Creative Nano team was looking to continuously monitor silicon carbide (SiC) nanoparticles in an electrolyte solution before using them for coatings within electroplating processes.
The challenges are:
from water analysis to research into soil composition and investigating pollutants
parenteral nutrition, painkillers, water for injections, therapeutic protein injectibles
understanding and optimizing protein-protein interactions, lipoproteins, VLPs, EVs, cell cultures
from suncreen to shampoo, skin creams to mouth wash
quality monitoring in the wet production of semiconductors
curiosity takes our partners to many places and results in wonderful discoveries
BRAVE ANALYTICS
Our expertise
As a partner in the MOZART project (MOZART for safe & sustainable by-design metallic coatings & engineered surfaces (RIA)), we received funding from the European Commission as part of the EU Horizon 2020 program.