Take a look at how OF2i® and our other BRAVE innovations are in use in biotech applications.
BRAVE Analytics’ nanoparticle analyzer and online particle sensor provide a way to determine when aggregation starts to occur. It monitors the progression of aggregation as it happens via OF2i® and static light scattering signals[1] and delivers results in real-time, eliminating the delay inherent in waiting for offline measurements.
Reference: [1] Imaging the scattered light of a nanoparticle through a cylindrical capillary. Ulrich Hohenester, Christian Neuper, Marko Šimić, and Christian Hill. Nanophotonics, 13(4):457–463, 2024.
These time-resolved measurements on different concentrations of proteins and RNA reveal the kinetics of LLPS processes and allow deeper insights than ever before.
The particle concentration of the fractions passing through the SEC column were continuously measured using the OF2i® static light scattering module. The results give insight into the properties of aggregated LDL versus non-aggregated LDL and also flagged which fractions where the purest and therefore best-suited for e.g. cryo-EM investigations.
from water analysis to research into soil composition and investigating pollutants
parenteral nutrition, painkillers, water for injections, therapeutic protein injectibles
understanding and optimizing protein-protein interactions, lipoproteins, VLPs, EVs, cell cultures
from suncreen to shampoo, skin creams to mouth wash
quality monitoring in the wet production of semiconductors
curiosity takes our partners to many places and results in wonderful discoveries
BRAVE ANALYTICS
Our expertise
As a partner in the MOZART project (MOZART for safe & sustainable by-design metallic coatings & engineered surfaces (RIA)), we received funding from the European Commission as part of the EU Horizon 2020 program.